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The stage is set for a compelling top-flight matchup as table-toppers Arsenal entertain rock-bottom Wolves to the Emirates Stadium.

Confirmed Sides

Arsenal have introduced a trio of alterations following the team that endured a 2-1 defeat at Aston Villa last weekend. The French defender, the Swedish striker and the Brazilian winger are all included in the lineup. The captain and the Spanish midfielder are named on the substitutes' bench, while Riccardo Calafiori is absent. Saliba is back after sitting out five matches due to injury.

Wolves also have made three adjustments to their lineup following being skelped 4-1 at Molineux by Manchester United on Monday evening. The experienced full-back, the Brazilian midfielder and Hwang Hee-chan are recalled. Ki-Jana Hoever and Arias drop to the substitutes, while Jean‐Ricner Bellegarde is omitted altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Subs: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Subs: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Referee: Robert Jones
Video Assistant Referee: John Brooks

Preamble

Welcome! And I mean, look at this …

The table tells a clear picture. The hosts sit proudly at the top of the Premier League, while their opponents anchor the division.

… yet while this will be the 42nd occasion the Premier League leaders have played the side propping up the entire table – winning 30 victories from 41, with seven draws – which team is responsible for two of the four all-time upsets? Indeed, Wolverhampton Wanderers, that’s who! So while the Arsenal manager will undoubtedly be expecting another three points, Rob Edwards must know that underdogs sometimes succeed, and you never know. The start is at 8 o'clock in the evening GMT. It’s on!

^{(The other two bottom-beats-top wins in the modern top-flight era are Oldham’s 1-0 win over United in March 1993, and Tottenham Hotspur – yeah, this one sounds a bit weird - beating Liverpool in November 2008.)}